Definitions for presenilins

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U.S. National Library of Medicine

  1. Presenilins

    Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PROTEIN precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.

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"presenilins." Definitions.net. STANDS4 LLC, 2014. Web. 20 Apr. 2014. <http://www.definitions.net/definition/presenilins>.

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