Definitions for presenilin-1
This page provides all possible meanings and translations of the word presenilin-1
U.S. National Library of Medicine
Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PROTEIN precursors. PSEN1 mutations cause early-onset ALZHEIMER DISEASE type 3 that may occur as early as 30 years of age in humans.
Find a translation for the presenilin-1 definition in other languages:
Select another language:
Discuss these presenilin-1 definitions with the community:
Use the citation below to add this definition to your bibliography:
"presenilin-1." Definitions.net. STANDS4 LLC, 2014. Web. 18 Apr. 2014. <http://www.definitions.net/definition/presenilin-1>.