Definitions for sideroblastic anemia
sider·ob·las·tic ane·mi·a

Princeton's WordNetRate this definition:0.0 / 0 votes

1. sideroblastic anemia, sideroblastic anaemia, siderochrestic anemia, siderochrestic anaemianoun

   refractory anemia characterized by sideroblasts in the bone marrow

WikipediaRate this definition:0.0 / 0 votes

1. Sideroblastic anemia

   Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need in order to transport oxygen efficiently. The disorder may be caused either by a genetic disorder or indirectly as part of myelodysplastic syndrome, which can develop into hematological malignancies (especially acute myeloid leukemia). Sideroblasts (sidero- + -blast) are nucleated erythroblasts (precursors to mature red blood cells) with granules of iron accumulated in the mitochondria surrounding the nucleus. Normally, sideroblasts are present in the bone marrow, and enter the circulation after maturing into a normal erythrocyte. The presence of sideroblasts per se does not define sideroblastic anemia. Only the finding of ring (or ringed) sideroblasts characterizes sideroblastic anemia. Ring sideroblasts are named so because iron-laden mitochondria form a ring around the nucleus. It is a subtype of basophilic granules of the erythrocyte, but which can only be seen in bone marrow. To count a cell as a ring sideroblast, the ring must encircle a third or more of the nucleus and contain five or more iron granules, according to the 2008 WHO classification of the tumors of the hematopoietic and lymphoid tissues.

ChatGPTRate this definition:0.0 / 0 votes

1. sideroblastic anemia

   Sideroblastic anemia is a group of blood disorders characterized by an inability of the bone marrow to produce normal, healthy red blood cells due to defective iron utilization, leading to the presence of ringed sideroblasts. This condition can be either inherited or acquired. It results in various symptoms including fatigue, weakness, shortness of breath, and increased iron levels in the body.

WikidataRate this definition:0.0 / 0 votes

1. Sideroblastic anemia

   Sideroblastic anemia or sideroachrestic anemia is a disease in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells. It may be caused either by a genetic disorder or indirectly as part of myelodysplastic syndrome, which can evolve into hematological malignancies. In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need to transport oxygen efficiently. Sideroblasts are atypical, abnormal nucleated erythroblasts with granules of iron accumulated in perinuclear mitochondria. Sideroblasts are seen in aspirates of bone marrow. Ring sideroblasts are named so because of the arrangement of the iron granules in a ring form around the nucleus. However it does not take the ring to be complete in order to count a cell as a ring sideroblast. According to the 2008 WHO classification of the tumors of the hematopoietic and lymphoid tissues, it only needs 5 or more iron granules encircling one third or more of the nucleus. The WHO International Working Group on Morphology of MDS defined three types of sideroblasts:

Matched Categories

1. • Refractory Anemia

How to pronounce sideroblastic anemia?

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Numerology

1. Chaldean Numerology

   The numerical value of sideroblastic anemia in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of sideroblastic anemia in Pythagorean Numerology is: 8

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=sideroblastic anemia
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Sideroblastic_Anemia
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=sideroblastic anemia