What does malignant hyperthermia mean?
Definitions for malignant hyperthermia
ma·lig·nan·t hy·per·ther·mi·a
This dictionary definitions page includes all the possible meanings, example usage and translations of the word malignant hyperthermia.
Princeton's WordNet
malignant hyperthermianoun
hereditary condition in which certain anesthetics (e.g., halothane) cause high body temperatures and muscle rigidity
Wikidata
Malignant hyperthermia
Malignant hyperthermia or malignant hyperpyrexia is a rare life-threatening condition that is usually triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine. In susceptible individuals, these drugs can induce a drastic and uncontrolled increase in skeletal muscle oxidative metabolism, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide, and regulate body temperature, eventually leading to circulatory collapse and death if not treated quickly. Susceptibility to MH is often inherited as an autosomal dominant disorder, for which there are at least 6 genetic loci of interest, most prominently the ryanodine receptor gene. MH susceptibility is phenotypically and genetically related to central core disease, an autosomal dominant disorder characterized both by MH symptoms and myopathy. MH is usually revealed by anesthesia, or when a family member develops the symptoms. There is no simple, straightforward test to diagnose the condition. When MH develops during a procedure, treatment with dantrolene sodium is usually initiated; dantrolene and the avoidance of anesthesia in susceptible people have markedly reduced the mortality from this condition.
U.S. National Library of Medicine
Malignant Hyperthermia
Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of malignant hyperthermia in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of malignant hyperthermia in Pythagorean Numerology is: 3
Translations for malignant hyperthermia
From our Multilingual Translation Dictionary
- злокачественная гипертермияRussian
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"malignant hyperthermia." Definitions.net. STANDS4 LLC, 2024. Web. 12 May 2024. <https://www.definitions.net/definition/malignant+hyperthermia>.
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