What does dna glycosylase mean?
Definitions for dna glycosylase
dna gly·co·sy·lase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word dna glycosylase.
Wikidata
DNA glycosylase
DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.2.2. Base excision repair is the mechanism by which damaged bases in DNA are removed and replaced. DNA glycosylases catalyze the first step of this process. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact, creating an apurinic/apyrimidinic site, commonly referred to as an AP site. This is accomplished by flipping the damaged base out of the double helix followed by cleavage of the N-glycosidic bond. Glycosylases were first discovered in bacteria, and have since been found in all kingdoms of life. In addition to their role in base excision repair DNA glycosylase enzymes have been implicated in the repression of gene silencing in A. thaliana, N. tabacum and other plants by active demethylation. 5-methylcytosine residues are excised and replaced with unmethylated cytosines allowing access to the chromatin structure of the enzymes and proteins necessary for trancription and subsequent translation.
Numerology
Chaldean Numerology
The numerical value of dna glycosylase in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of dna glycosylase in Pythagorean Numerology is: 9
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"dna glycosylase." Definitions.net. STANDS4 LLC, 2024. Web. 28 Apr. 2024. <https://www.definitions.net/definition/dna+glycosylase>.
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