What does cooley's anaemia mean?

Definitions for cooley's anaemia
coo·ley's anaemi·a

This dictionary definitions page includes all the possible meanings, example usage and translations of the word cooley's anaemia.

Princeton's WordNet

  1. Cooley's anemia, Cooley's anaemia, thalassemia major, thalassaemia majornoun

    a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged

Wikipedia

  1. cooley's anaemia

    Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are forms of thalassemia caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals. Global annual incidence is estimated at one in 100,000. Beta thalassemias occur due to malfunctions in the hemoglobin subunit beta or HBB. The severity of the disease depends on the nature of the mutation.HBB blockage over time leads to decreased beta-chain synthesis. The body's inability to construct new beta-chains leads to the underproduction of HbA (adult hemoglobin). Reductions in HbA available overall to fill the red blood cells in turn leads to microcytic anemia. Microcytic anemia ultimately develops in respect to inadequate HBB protein for sufficient red blood cell functioning. Due to this factor, the patient may require blood transfusions to make up for the blockage in the beta-chains. Repeated blood transfusions cause severe problems associated with iron overload.

ChatGPT

  1. cooley's anaemia

    Cooley's Anemia, also known as Thalassemia Major, is a severe genetic blood disorder characterized by a marked deficiency in producing hemoglobin, the protein in red blood cells that carries oxygen. This can lead to anemia, fatigue, growth retardation, bone deformities, and other serious health complications. The condition is most common among people of Italian, Greek, Middle Eastern, South Asian, and African descent.

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Numerology

  1. Chaldean Numerology

    The numerical value of cooley's anaemia in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of cooley's anaemia in Pythagorean Numerology is: 3

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"cooley's anaemia." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/cooley%27s+anaemia>.

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