What does cooley's anemia mean?
Definitions for cooley's anemia
ˈku lizcoo·ley's ane·mi·a
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cooley's anemia.
Princeton's WordNet
Cooley's anemia, Cooley's anaemia, thalassemia major, thalassaemia majornoun
a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged
Wikipedia
cooley's anemia
Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are forms of thalassemia caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals. Global annual incidence is estimated at one in 100,000. Beta thalassemias occur due to malfunctions in the hemoglobin subunit beta or HBB. The severity of the disease depends on the nature of the mutation.HBB blockage over time leads to decreased beta-chain synthesis. The body's inability to construct new beta-chains leads to the underproduction of HbA (adult hemoglobin). Reductions in HbA available overall to fill the red blood cells in turn leads to microcytic anemia. Microcytic anemia ultimately develops in respect to inadequate HBB protein for sufficient red blood cell functioning. Due to this factor, the patient may require blood transfusions to make up for the blockage in the beta-chains. Repeated blood transfusions cause severe problems associated with iron overload.
ChatGPT
cooley's anemia
Cooley's anemia, also known as thalassemia major, is a genetic disorder resulting in the inability to produce normal, functional hemoglobin, the protein in red blood cells that carries oxygen. It is characterized by severe anemia, increased iron accumulation in the body, and other complications including bone deformities and enlarged spleen. Symptoms typically appear in early childhood. Treatment usually involves regular blood transfusions and iron chelation therapy to remove excess iron from the body.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of cooley's anemia in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of cooley's anemia in Pythagorean Numerology is: 2
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"cooley's anemia." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/cooley%27s+anemia>.
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