a narcotic (alkaloid) extracted from coca leaves; used as a surface anesthetic or taken for pleasure; can become powerfully addictive
A powerful narcotic alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain. It is classified as addictive and is not available in the U. S. without a prescription, but is nevertheless one of the most widespread illegal drugs of abuse. It is used in several forms, including small pellets of free base, called crack. Most of the cacaine illegally used in the U.S. is imported.
A stimulant narcotic in the form of a white powder that users generally self-administer by insufflation through the nose.
Etymology: From kuka, probably via cocaïne.
Any derivative of cocaine.
Etymology: From kuka, probably via cocaïne.
a powerful alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" and the alkaloid suffix -ine, forming cocaine. It is a stimulant, an appetite suppressant, and a topical anesthetic. Biologically, cocaine acts as a serotonin–norepinephrine–dopamine reuptake inhibitor, also known as a triple reuptake inhibitor. It is addictive because of its effect on the mesolimbic reward pathway. Unlike most molecules, cocaine has pockets with both high hydrophilic and lipophilic efficiency, violating the rule of hydrophilic-lipophilic balance. This causes it to cross the blood–brain barrier far better than other psychoactive chemicals and may even induce blood-brain barrier breakdown. It is controlled internationally by Single Convention on Narcotic Drugs.
The Nuttall Encyclopedia
an alkaloid from the leaf of the coca plant, used as an anæsthetic.
U.S. National Library of Medicine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
The numerical value of cocaine in Chaldean Numerology is: 7
The numerical value of cocaine in Pythagorean Numerology is: 5
It's not like we're talking about cocaine or heroin here, we're talking about a Napa Valley Cabernet Sauvignon from the 2012 vintage.
You assume these guys are dropping dead because of what goes on in the ring, but it’s not true. Most of that is staged, occasionally someone gets hurt in the ring… the real reason they die young is because a lot of them are drug addicts, a lot of them are taking cocaine, they bulk up using steroids and it puts a big strain on the heart. They are always under the stress of this performance. They don’t have a natural life; they are always hyped up and they are always trying to calm down.
In 2020 we also seized more than 500 tonnes of cocaine hydrochloride, another objective we are keeping for 2021. The fight against drugs will continue to be a key focus and will continue to combine all the available tools.
I didn't drink to party, alcohol and cocaine were private things to me. I would use them for work.
However, rising deaths from synthetic opioids -- as well as from cocaine and methamphetamine -- represent the next disturbing wave of the nation's ongoing substance use challenge.
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Translations for cocaine
From our Multilingual Translation Dictionary
- nííʼiiʼniłíNavajo, Navaho
- кокаин, kokainSerbo-Croatian
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