a narcotic (alkaloid) extracted from coca leaves; used as a surface anesthetic or taken for pleasure; can become powerfully addictive
A powerful narcotic alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain. It is classified as addictive and is not available in the U. S. without a prescription, but is nevertheless one of the most widespread illegal drugs of abuse. It is used in several forms, including small pellets of free base, called crack. Most of the cacaine illegally used in the U.S. is imported.
A stimulant narcotic in the form of a white powder that users generally self-administer by insufflation through the nose.
Any derivative of cocaine.
Origin: From kuka, probably via cocaïne.
a powerful alkaloid, C17H21NO4, obtained from the leaves of coca. It is a bitter, white, crystalline substance, and is remarkable for producing local insensibility to pain
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" and the alkaloid suffix -ine, forming cocaine. It is a stimulant, an appetite suppressant, and a topical anesthetic. Biologically, cocaine acts as a serotonin–norepinephrine–dopamine reuptake inhibitor, also known as a triple reuptake inhibitor. It is addictive because of its effect on the mesolimbic reward pathway. Unlike most molecules, cocaine has pockets with both high hydrophilic and lipophilic efficiency, violating the rule of hydrophilic-lipophilic balance. This causes it to cross the blood–brain barrier far better than other psychoactive chemicals and may even induce blood-brain barrier breakdown. It is controlled internationally by Single Convention on Narcotic Drugs.
The Nuttall Encyclopedia
an alkaloid from the leaf of the coca plant, used as an anæsthetic.
U.S. National Library of Medicine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
The numerical value of cocaine in Chaldean Numerology is: 7
The numerical value of cocaine in Pythagorean Numerology is: 5
Examples of cocaine in a Sentence
He is the last of the Cocaine Cowboys.
He was the last of the Cocaine Cowboys.
Cocaine was a lot easier to kick than cigarettes.
At least when I was govenor, cocaine was expensive.
She knew I was doing cocaine the whole time after that.
Images & Illustrations of cocaine
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Translations for cocaine
From our Multilingual Translation Dictionary
- nííʼiiʼniłíNavajo, Navaho
- кокаин, kokainSerbo-Croatian
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