What does cleavage stimulation factor mean?
Definitions for cleavage stimulation factor
cleav·age stim·u·la·tion fac·tor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cleavage stimulation factor.
Wikipedia
Cleavage stimulation factor
Cleavage stimulatory factor or cleavage stimulation factor (CstF or CStF) is a heterotrimeric protein, made up of the proteins CSTF1 (55kDa), CSTF2 (64kDa) and CSTF3 (77kDa), totalling about 200 kDa. It is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA (mRNA) molecule. CstF is recruited by cleavage and polyadenylation specificity factor (CPSF) and assembles into a protein complex on the 3' end to promote the synthesis of a functional polyadenine tail, which results in a mature mRNA molecule ready to be exported from the cell nucleus to the cytosol for translation. The amount of CstF in a cell is dependent on the phase of the cell cycle, increasing significantly during the transition from G0 phase to S phase in mouse fibroblast and human splenic B cells.
U.S. National Library of Medicine
Cleavage Stimulation Factor
A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
Numerology
Chaldean Numerology
The numerical value of cleavage stimulation factor in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of cleavage stimulation factor in Pythagorean Numerology is: 2
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"cleavage stimulation factor." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/cleavage+stimulation+factor>.
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