Definitions for varenicline
vareni·cline

WiktionaryRate this definition:0.0 / 0 votes

1. vareniclinenoun

   A particular pharmaceutical drug, an agonist for nicotine, used to aid tobacco-smoking cessation.

WikipediaRate this definition:0.0 / 0 votes

1. Varenicline

   Varenicline (trade name Chantix and Champix) is a medication used for smoking cessation. Varenicline is also used for the treatment of dry eye disease.The most common side-effects include nausea (feeling sick), insomnia (difficulty sleeping), abnormal dreams, headache and nasopharyngitis (inflammation of the nose and throat).It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACh) that leads to the release of the neurotransmitter dopamine in the nucleus accumbens reward center of the brain when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation. In this respect it is similar to cytisine and different from the nicotinic antagonist bupropion and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. It is estimated that varenicline successfully helps one of every eleven people who smoke remain abstinent from tobacco at six months.It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 275th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

WikidataRate this definition:0.0 / 0 votes

1. Varenicline

   Varenicline, is a prescription medication used to treat smoking addiction. Varenicline is a nicotinic receptor partial agonist - it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies like nicotine patches and nicotine gum. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can assist some patients to quit smoking.

How to pronounce varenicline?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say varenicline in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of varenicline in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of varenicline in Pythagorean Numerology is: 4

Examples of varenicline in a Sentence

1. Nicola Lindson-Hawley:

   There is a lot of evidence to suggest that if you would like to quit the best way to do so is by seeking help in the form of behavioral counseling and a treatment such as nicotine replacement therapy (i.e. patches or gum) or varenicline, however, there are also benefits of calling quitlines, particularly if these go on to provide proactive support for quitters.

2. Daniel Kotz:

   Smokers typically lose three months of life expectancy for every year of continued smoking, our research supports the use of varenicline as an effective and safe tool to help people quit.

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Varenicline
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Varenicline
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=varenicline