What does tumor suppressor protein p53 mean?
Definitions for tumor suppressor protein p53
tumor sup·pressor protein p53
This dictionary definitions page includes all the possible meanings, example usage and translations of the word tumor suppressor protein p53.
Wikipedia
tumor suppressor protein p53
p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers. The p53 proteins (originally thought to be, and often spoken of as, a single protein) are crucial in vertebrates, where they prevent cancer formation. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. Hence TP53 is classified as a tumor suppressor gene.The TP53 gene is the most frequently mutated gene (>50%) in human cancer, indicating that the TP53 gene plays a crucial role in preventing cancer formation. TP53 gene encodes proteins that bind to DNA and regulate gene expression to prevent mutations of the genome. In addition to the full-length protein, the human TP53 gene encodes at least 15 protein isoforms.
U.S. National Library of Medicine
Tumor Suppressor Protein p53
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Numerology
Chaldean Numerology
The numerical value of tumor suppressor protein p53 in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of tumor suppressor protein p53 in Pythagorean Numerology is: 6
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"tumor suppressor protein p53." Definitions.net. STANDS4 LLC, 2024. Web. 27 Apr. 2024. <https://www.definitions.net/definition/tumor+suppressor+protein+p53>.
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