Definitions for transaminase
trænsˈæm əˌneɪs, -ˌneɪz, trænz-transam·i·nase

Princeton's WordNetRate this definition:0.0 / 0 votes

1. transaminase, aminotransferase, aminopherasenoun

   a class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound)

WiktionaryRate this definition:0.0 / 0 votes

1. transaminasenoun

   Any of a group of enzymes that catalyzes transamination.

WikipediaRate this definition:0.0 / 0 votes

1. Transaminase

   Transaminases or aminotransferases are enzymes that catalyze a transamination reaction between an amino acid and an α-keto acid. They are important in the synthesis of amino acids, which form proteins.

ChatGPTRate this definition:0.0 / 0 votes

1. transaminase

   Transaminase is a type of enzyme that plays a key role in amino acid metabolism, responsible for facilitating the transfer of an amino group from one molecule to another. Elevated levels of transaminase can indicate liver damage or disease. There are several types of transaminases, including alanine transaminase (ALT) and aspartate transaminase (AST), which are commonly measured as part of liver function tests.

WikidataRate this definition:0.0 / 0 votes

1. Transaminase

   In biochemistry, a transaminase or an aminotransferase is an enzyme that catalyzes a type of reaction between an amino acid and an α-keto acid. An amino acid contains an amine group. A keto acid contains a keto group. In transamination, the NH2 group on one molecule is exchanged with the =O group on the other molecule. The amino acid becomes a keto acid, and the keto acid becomes an amino acid. Some transamination activities of the ribosome have been found to be catalyzed by so-called ribozymes. Examples being the hammerhead ribozyme, the VS ribozyme and the hairpin ribozyme. The transaminase enzymes are important in the production of various amino acids, and measuring the concentrations of various transaminases in the blood is important in the diagnosing and tracking many diseases. Transaminases require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid. Enzyme-bound pyridoxamine in turn reacts with pyruvate, oxaloacetate, or alpha-ketoglutarate, giving alanine, aspartic acid, or glutamic acid, respectively. Many transamination reactions occur in tissues, catalysed by transaminases specific for a particular amino/keto acid pair. The reactions are readily reversible, the direction being determined by which of the reactants are in excess. The specific enzymes are named from one of the reactant pairs, for example; the reaction between glutamic acid and pyruvic acid to make alpha ketoglutaric acid and alanine is called glutamic-pyruvic transaminase or GPT for short. Tissue transaminase activities can be investigated by incubating a homogenate with various amino/keto aci dpairs. Transamination is demonstrated if the corresponding new amino acid and keto acid are formed, as revealed by paper chromatography. Reversibility is demonstrated by using the complementary keto/amino acid pari as starting reactants. After chromatogram has been taken out of the solvent the chromatogram is then treated with ninhydrin to locate the spots.

Editors ContributionRate this definition:0.0 / 0 votes

1. transaminase

   A type of enzyme.

   Transaminase are a group of enzymes that catalyze transamination.

   
   

   Submitted by MaryC on April 22, 2020  

Matched Categories

1. • Transferase

How to pronounce transaminase?

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Numerology

1. Chaldean Numerology

   The numerical value of transaminase in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of transaminase in Pythagorean Numerology is: 8

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=transaminase
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Transaminase
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Transaminase
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=transaminase