What does syntrophin mean?
Definitions for syntrophin
syn·trophin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word syntrophin.
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Wiktionary
syntrophinnoun
Any of a class of proteins that are associated with dystrophin
Wikidata
Syntrophin
The syntrophins are a family of five 60-kiloDalton proteins that are associated with dystrophin, the protein associated with Duchenne muscular dystrophy and Becker muscular dystrophy. The name comes from the Greek word syntrophos, meaning "companion." The five syntrophins are encoded by separate genes and are termed α, β1, β2, γ1, and γ2. Syntrophin was first identified as a dystrophin-associated protein present in torpedo electric organ. Subsequently, alpha syntrophin was shown to be the predominant isoform in skeletal muscle where it is localized on the sarcolemma and enriched at the neuromuscular junction. The beta syntrophins and γ2 syntrophin are also present in skeletal muscle but also are in most other tissues. The expression of γ1 syntrophin is mostly confined to brain. The syntrophins are adapter proteins that use their multiple protein interaction domains to localize a variety of signaling proteins to specific intracellular locations. α-Syntrophin binds to nNOS in the dystrophin associated glycoprotein complex in skeletal muscle cells. There it produces NO upon muscle contraction leading to dilation of the arteries in the local area.
Numerology
Chaldean Numerology
The numerical value of syntrophin in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of syntrophin in Pythagorean Numerology is: 5
Translations for syntrophin
From our Multilingual Translation Dictionary
- συντροφίνηGreek
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"syntrophin." Definitions.net. STANDS4 LLC, 2024. Web. 27 Apr. 2024. <https://www.definitions.net/definition/syntrophin>.
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