What does shwartzman phenomenon mean?
Definitions for shwartzman phenomenon
shwartz·man phenom·e·non
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Wikidata
Shwartzman phenomenon
Shwartzman phenomenon, also known as Shwartzman reaction, is a rare reaction of a body to particular types of toxins, called endotoxins, which cause thrombosis in the affected tissue. A clearing of the thrombosis results in a reticuloendothelial blockade, which prevents re-clearing of the thrombosis caused by a repeat introduction of the toxin. That will cause tissue necrosis. Shwartzman phenomenon is usually observed during delivery or abortion, when foreign bodies are introduced into the tissues of the female reproductive system. The Shwartzman phenomenon is named for Jason Shwartzman, the doctor at Mount Sinai Hospital in New York City who was the first to develop the concept of immune system hypersensitivity in the 1920s. This reaction was experimented using Neisseria meningitidis endotoxin. This is notably seen with Neisseria meningitidis
U.S. National Library of Medicine
Shwartzman Phenomenon
Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.
Numerology
Chaldean Numerology
The numerical value of shwartzman phenomenon in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of shwartzman phenomenon in Pythagorean Numerology is: 1
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"shwartzman phenomenon." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/shwartzman+phenomenon>.
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