What does shine-dalgarno sequence mean?
Definitions for shine-dalgarno sequence
shine-dal·gar·no sequence
This dictionary definitions page includes all the possible meanings, example usage and translations of the word shine-dalgarno sequence.
Wiktionary
Shine-Dalgarno sequencenoun
A ribosomal binding site in the mRNA of prokaryotes.
Etymology: After Australian scientists John Shine and Lynn Dalgarno.
Wikipedia
shine-dalgarno sequence
The Shine–Dalgarno (SD) sequence is a ribosomal binding site in bacterial and archaeal messenger RNA, generally located around 8 bases upstream of the start codon AUG. The RNA sequence helps recruit the ribosome to the messenger RNA (mRNA) to initiate protein synthesis by aligning the ribosome with the start codon. Once recruited, tRNA may add amino acids in sequence as dictated by the codons, moving downstream from the translational start site. The Shine–Dalgarno sequence is common in bacteria, but rarer in archaea. It is also present in some chloroplast and mitochondrial transcripts. The six-base consensus sequence is AGGAGG; in Escherichia coli, for example, the sequence is AGGAGGU, while the shorter GAGG dominates in E. coli virus T4 early genes.The Shine–Dalgarno sequence was proposed by Australian scientists John Shine and Lynn Dalgarno.
Wikidata
Shine-Dalgarno sequence
The Shine-Dalgarno sequence, proposed by Australian scientists John Shine and Lynn Dalgarno, is a ribosomal binding site in the mRNA, generally located 8 bases upstream of the start codon AUG. The Shine-Dalgarno sequence exists both in bacteria and archaea, being also present in some chloroplastic and mitochondial transcripts. The six-base consensus sequence is AGGAGG; in E. coli, for example, the sequence is AGGAGGU. This sequence helps recruit the ribosome to the mRNA to initiate protein synthesis by aligning it with the start codon. The complementary sequence, is called the anti-Shine-Dalgarno sequence and is located at the 3' end of the 16S rRNA in the ribosome. The eukaryotic equivalent of the Shine-Dalgarno sequence is called the Kozak sequence. Mutations in the Shine-Dalgarno sequence can reduce or increase translation. This change is due to a reduced or increased mRNA-ribosome pairing efficiency, as evidenced by the fact that complementary mutations in the anti-Shine-Dalgarno sequence can restore translation. The Shine-Dalgarno sequence GAGG dominates in bacteriophage T4 early genes, whereas the sequence GGAG is a target for the T4 endonuclease RegB that initiates the early mRNA degradation.
Numerology
Chaldean Numerology
The numerical value of shine-dalgarno sequence in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of shine-dalgarno sequence in Pythagorean Numerology is: 9
Translations for shine-dalgarno sequence
From our Multilingual Translation Dictionary
- sequência shine-dalgarnoPortuguese
- parlaklık-dalgarno dizisiTurkish
- چمک ڈالگونو ترتیبUrdu
Get even more translations for shine-dalgarno sequence »
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"shine-dalgarno sequence." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/shine-dalgarno+sequence>.
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