What does serum response factor mean?

Definitions for serum response factor
serum re·sponse fac·tor

This dictionary definitions page includes all the possible meanings, example usage and translations of the word serum response factor.

Wikidata

  1. Serum response factor

    Serum response factor, also known as SRF, is a transcription factor. It is a member of the MADS box superfamily of transcription factors. This protein binds to the serum response element in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway that acts through the ternary complex factors. SRF is considered very important during the development of the embryo, as it has been linked to the formation of mesoderm. In the fully developed mammal, SRF is crucial for the growth of skeletal muscle. Interaction of SRF with other proteins, such as steroid hormone receptors, may contribute to regulation of muscle growth by steroids. Lack of skin SRF is associated with psoriasis and other skin diseases.

U.S. National Library of Medicine

  1. Serum Response Factor

    A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.

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Numerology

  1. Chaldean Numerology

    The numerical value of serum response factor in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of serum response factor in Pythagorean Numerology is: 7

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"serum response factor." Definitions.net. STANDS4 LLC, 2024. Web. 18 Mar. 2024. <https://www.definitions.net/definition/serum+response+factor>.

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