What does secretase mean?
Definitions for secretase
sec·re·tase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word secretase.
Princeton's WordNet
secretasenoun
a set of enzymes believed to snip pieces off a longer protein producing fragments of amyloid protein that bunch up and create amyloid protein plaques in brain tissue (the pathological hallmark of Alzheimer's)
Wiktionary
secretasenoun
An enzyme that "snips" pieces off a longer protein that is embedded in the cell membrane.
Wikipedia
secretase
Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane. Among other roles in the cell, secretases act on the amyloid-beta precursor protein (APP) to cleave the protein into three fragments. Sequential cleavage by beta-secretase 1 (BACE) and gamma-secretase (γ-secretase) produces the amyloid-beta peptide fragment that aggregates into clumps called amyloid plaques in the brains affected by Alzheimer's disease. If alpha-secretase (α-secretase) acts on APP first instead of BACE, no amyloid beta is formed because α-secretase recognizes a target protein sequence closer to the cell surface than BACE. The non-pathogenic middle fragment formed by an α/γ cleavage sequence is called P3.
ChatGPT
secretase
Secretase is a type of enzyme that functions in processing certain proteins. They are involved in several cellular activities such as the immune defense response and transmembrane protein signal transduction, with particular roles in cleaving proteins, specifically amyloid precursor protein, into smaller fragments. The improper functioning or mutation of secretases is believed to contribute to certain diseases, such as Alzheimer's disease.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of secretase in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of secretase in Pythagorean Numerology is: 5
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"secretase." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/secretase>.
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