What does saralasin mean?
Definitions for saralasin
sar·alasin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word saralasin.
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Wikidata
Saralasin
Saralasin is a partial agonist of angiotensin II receptors, though It is commonly mistaken as a competitive antagonist. Saralasin's distinction as a partial agonist is based on the fact that it's therapeutic effect is only observed in patients with high plasma angiotensin II levels, but in patients with low angiotensin II levels Saralasin causes hypertension. In other words, the effects of Saralasin on the angiotensin II receptor in the absence of angiotensin II is pharmacodynamically similar to angiotensin II itself thus it is a partial agonist, because if it was an antagonist it would not elicit an effect when bound to its receptor. Saralasin is an angiotensin II analogue, containing sarcosine-1 and alanine-8, hence the name.
U.S. National Library of Medicine
Saralasin
An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific competitive inhibitor of angiotensin II.
Numerology
Chaldean Numerology
The numerical value of saralasin in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of saralasin in Pythagorean Numerology is: 4
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"saralasin." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/saralasin>.
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