What does retinoblastoma protein mean?
Definitions for retinoblastoma protein
retinoblas·toma pro·tein
This dictionary definitions page includes all the possible meanings, example usage and translations of the word retinoblastoma protein.
Wiktionary
retinoblastoma proteinnoun
A protein, whose inactivation by mutation leads to the formation of retinoblastomas
Wikidata
Retinoblastoma protein
The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in several major cancers. One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. It is also a recruiter of several chromatin remodeling enzymes such as methylases and acetylases. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer.
U.S. National Library of Medicine
Retinoblastoma Protein
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Numerology
Chaldean Numerology
The numerical value of retinoblastoma protein in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of retinoblastoma protein in Pythagorean Numerology is: 9
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"retinoblastoma protein." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/retinoblastoma+protein>.
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