What does prostaglandin d2 mean?
Definitions for prostaglandin d2
prostaglandin d2
This dictionary definitions page includes all the possible meanings, example usage and translations of the word prostaglandin d2.
Wikidata
Prostaglandin D2
Prostaglandin D2 is a prostaglandin that binds to the receptor PTGDR, as well as CRTH2. It is a major prostaglandin produced by mast cells – recruits Th2 cells, eosinophils, and basophils. In mammalian organs, large amounts of PGD2 are found only in the brain and in mast cells. It is critical to development of allergic diseases such as asthma. Research carried out in 1989 found PGD2 is the primary mediator of vasodilation after ingestion of niacin. A 2012 research paper indicates a causal link between elevated levels of localized prostaglandin D2 and hair growth inhibition. Applied topically, the research found PGD2 prevents hair growth, and mice that were genetically inclined to produce higher levels of PGD2 had inhibited hair growth. The research also found PGD2 levels were much higher in balding scalp tissue than nonbalding scalp tissue. The paper suggested one of the receptors involved in production of PGD2, GPR44, would therefore be a therapeutic target for androgenic alopecia in both men and women with hair loss and thinning. Because PGD2's relation to asthma has been known for several years, several drugs that seek to reduce PGD2 levels through blocking the GPR44 level are already in clinical trials.
U.S. National Library of Medicine
Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Numerology
Chaldean Numerology
The numerical value of prostaglandin d2 in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of prostaglandin d2 in Pythagorean Numerology is: 1
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"prostaglandin d2." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/prostaglandin+d2>.
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