What does properdin mean?
Definitions for properdin
prop·erdin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word properdin.
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Wiktionary
properdinnoun
A protein in human serum that complements part of the immune system
Wikipedia
Properdin
Properdin is protein that in humans is encoded by the CFP (complement factor properdin) gene. Properdin is plasma glycoprotein that activates the complement system of the innate immune system. This protein binds to bacterial cell walls and dying human cells to stabilize the C3 and C5-convertase enzyme complexes to form an attack complex that lead to the lysis of the cell.
Wikidata
Properdin
Properdin or Factor P is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases. It is found in the blood serum of more complex animals.
U.S. National Library of Medicine
Properdin
A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
Numerology
Chaldean Numerology
The numerical value of properdin in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of properdin in Pythagorean Numerology is: 7
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"properdin." Definitions.net. STANDS4 LLC, 2024. Web. 4 May 2024. <https://www.definitions.net/definition/properdin>.
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