Definitions for primidone
prim·i·done

Princeton's WordNetRate this definition:0.0 / 0 votes

1. primidone, Mysolinenoun

   an anticonvulsant (trade name Mysoline) used to treat grand mal seizures and essential tremor

WiktionaryRate this definition:0.0 / 0 votes

1. primidonenoun

   An anticonvulsant of the pyrimidinedione class whose active metabolites, phenobarbital and phenylethylmalonamide, are also anticonvulsants.

WikipediaRate this definition:0.0 / 0 votes

1. Primidone

   Primidone, sold under various brand names, is a barbiturate medication that is used to treat partial and generalized seizures, as well as essential tremors. It is taken by mouth.Common side effects include sleepiness, poor coordination, nausea, and loss of appetite. Severe side effects may include suicide, psychosis, a lack of blood cells. Use during pregnancy may result in harm to the baby. Primidone is an anticonvulsant of the barbiturate class. How it works is not entirely clear.Primidone was approved for medical use in the United States in 1954. It is available as a generic medication. In 2020, it was the 269th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

WikidataRate this definition:0.0 / 0 votes

1. Primidone

   Primidone is an anticonvulsant of the pyrimidinedione class, the active metabolites of which, phenobarbital and phenylethylmalonamide, are also anticonvulsants. It is used mainly to treat complex partial, simple partial, generalized tonic-clonic seizures, myoclonic, and akinetic seizures. Since the 1980s it has been a valuable alternative to propranolol in the treatment of essential tremor. Unlike other anticonvulsants such as carbamazepine and valproic acid, primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem, although this presents a risk for the worsening of some disorders. It is also occasionally used in treatment of neuropathic pain, trigeminal neuralgia, and migraine. Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis. Primidone was once a mainstay anticonvulsant in the treatment of partial and generalized seizures and was the treatment of choice for secondarily generalized seizures originating in the temporal lobes, especially when combined with phenytoin, but by the early 1980s, carbamazepine had surpassed it in popularity due to the latter's lower incidence of sedation. As time passed and more and more anticonvulsants came on the market, primidone was pushed further and further away from its former place of prominence and major Western pharmaceutical corporations became less and less interested in manufacturing and selling it. It has largely fallen into disuse in the developed world as more and more anticonvulsants entered the market and has been withdrawn from markets all over the world.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Primidone

   An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)

Matched Categories

1. • Anticonvulsant

How to pronounce primidone?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say primidone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of primidone in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of primidone in Pythagorean Numerology is: 4

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=primidone
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Primidone
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Primidone
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=primidone