U.S. National Library of Medicine
Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PROTEIN precursors. PSEN1 mutations cause early-onset ALZHEIMER DISEASE type 3 that may occur as early as 30 years of age in humans.
The numerical value of presenilin-1 in Chaldean Numerology is: 2
The numerical value of presenilin-1 in Pythagorean Numerology is: 4
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"presenilin-1." Definitions.net. STANDS4 LLC, 2019. Web. 23 Jan. 2019. <https://www.definitions.net/definition/presenilin-1>.