What does polygenic disorder mean?
Definitions for polygenic disorder
po·ly·genic dis·or·der
This dictionary definitions page includes all the possible meanings, example usage and translations of the word polygenic disorder.
Princeton's WordNet
polygenic disorder, polygenic diseasenoun
an inherited disease controlled by several genes at once
Wikipedia
polygenic disorder
Multifactorial diseases are not confined to any specific pattern of single gene inheritance and are likely to be caused when multiple genes come together along with the effects of environmental factors.In fact, the terms ‘multifactorial’ and ‘polygenic’ are used as synonyms and these terms are commonly used to describe the architecture of disease causing genetic component. Although multifactorial diseases are often found gathered in families yet, they do not show any distinct pattern of inheritance. It is difficult to study and treat multifactorial diseases because specific factors associated with these diseases have not yet been identified. Some common multifactorial disorders include schizophrenia, diabetes, asthma, depression, high blood pressure, Alzheimer’s, obesity, epilepsy, heart diseases, Hypothyroidism, club foot and even dandruff. The Multifactorial threshold model assumes that gene defects for multifactorial traits are usually distributed within populations. Firstly, different populations might have different thresholds. This is the case in which occurrences of a particular disease is different in males and females (e.g. Pyloric stenosis). The distribution of susceptibility is the same but threshold is different. Secondly, threshold may be same but the distributions of susceptibility may be different. It explains the underlying risks present in first degree relatives of affected individuals.
ChatGPT
polygenic disorder
A polygenic disorder is a disease or condition that is caused by the combined effect of mutations in multiple genes, often in addition to environmental factors. These disorders have complex characteristics and may exhibit a wide range of symptoms or manifestations. This concept is in contrast to monogenic disorders, which are caused by mutations in a single gene. Examples of polygenic disorders include diabetes, heart disease, and high blood pressure.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of polygenic disorder in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of polygenic disorder in Pythagorean Numerology is: 9
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"polygenic disorder." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/polygenic+disorder>.
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