What does parallel artificial membrane permeability assay mean?
Definitions for parallel artificial membrane permeability assay
par·al·lel ar·ti·fi·cial mem·brane per·me·abil·i·ty as·say
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Wikipedia
Parallel artificial membrane permeability assay
In medicinal chemistry, parallel artificial membrane permeability assay (PAMPA) is a method which determines the permeability of substances from a donor compartment, through a lipid-infused artificial membrane into an acceptor compartment. A multi-well microtitre plate is used for the donor and a membrane/acceptor compartment is placed on top; the whole assembly is commonly referred to as a “sandwich”. At the beginning of the test, the drug is added to the donor compartment, and the acceptor compartment is drug-free. After an incubation period which may include stirring, the sandwich is separated and the amount of drug is measured in each compartment. Mass balance allows calculation of drug that remains in the membrane.
Numerology
Chaldean Numerology
The numerical value of parallel artificial membrane permeability assay in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of parallel artificial membrane permeability assay in Pythagorean Numerology is: 4
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"parallel artificial membrane permeability assay." Definitions.net. STANDS4 LLC, 2024. Web. 27 Apr. 2024. <https://www.definitions.net/definition/parallel+artificial+membrane+permeability+assay>.
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