U.S. National Library of Medicine
A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to P-GLYCOPROTEIN. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
The numerical value of p-glycoproteins in Chaldean Numerology is: 6
The numerical value of p-glycoproteins in Pythagorean Numerology is: 5
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"p-glycoproteins." Definitions.net. STANDS4 LLC, 2018. Web. 20 Nov. 2018. <https://www.definitions.net/definition/p-glycoproteins>.