What does ochronosis mean?
Definitions for ochronosis
ochrono·sis
This dictionary definitions page includes all the possible meanings, example usage and translations of the word ochronosis.
Princeton's WordNet
ochronosisnoun
an accumulation of dark pigment in cartilage and other connective tissue; usually a symptom of alkaptonuria or phenol poisoning
Wiktionary
ochronosisnoun
An autosomal-recessive metabolic disorder that causes an excess of homogentisic acid, resulting in adverse pigmentation, calcification, and inflammation of cartilaginous and related tissue throughout the body.
Wikipedia
Ochronosis
Ochronosis is a syndrome caused by the accumulation of homogentisic acid in connective tissues. The condition was named after the yellowish (ocher-like) discoloration of the tissue seen on microscopic examination. Macroscopically, though, the affected tissues appear bluish-grey because of a light-scattering phenomenon known as the Tyndall effect. The condition is most often associated with alkaptonuria, but can occur from exogenous administration of phenol complexes such as hydroquinone. It was first described by Rudolf Virchow in 1865.
ChatGPT
ochronosis
Ochronosis is a rare metabolic disorder characterized by a buildup of a dark pigment in connective tissues, often in the skin and cartilage. It is typically associated with the inherited disorder alkaptonuria, which impacts the body's ability to process certain amino acids, leading to a buildup of a substance called homogentisic acid that can darken the skin and affect various parts of the body, such as the heart, kidneys, and bones.
Wikidata
Ochronosis
Ochronosis is the syndrome caused by the accumulation of homogentisic acid in connective tissues. The phenomenon was first described by Rudolf Virchow in 1865. The condition was named after the yellowish discoloration of the tissue seen on microscopic examination. However, macroscopically the affected tissues appear bluish grey because of a light scattering phenomenon known as the Tyndall effect. The condition is most often associated with alkaptonuria but can occur from exogenous administration of phenol complexes like hydroquinone.
U.S. National Library of Medicine
Ochronosis
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
Matched Categories
Numerology
Chaldean Numerology
The numerical value of ochronosis in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of ochronosis in Pythagorean Numerology is: 9
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"ochronosis." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/ochronosis>.
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