What does myocardial stunning mean?
Definitions for myocardial stunning
my·ocar·dial stun·ning
This dictionary definitions page includes all the possible meanings, example usage and translations of the word myocardial stunning.
Wikipedia
Myocardial stunning
Myocardial stunning or transient post-ischemic myocardial dysfunction is a state of mechanical cardiac dysfunction that can occur in a portion of myocardium without necrosis after a brief interruption in perfusion, despite the timely restoration of normal coronary blood flow. In this situation, even after ischemia has been relieved (by for instance angioplasty or coronary artery bypass surgery) and myocardial blood flow (MBF) returns to normal, myocardial function is still depressed for a variable period of time, usually days to weeks. This reversible reduction of function of heart contraction after reperfusion is not accounted for by tissue damage or reduced blood flow, but rather, its thought to represent a perfusion-contraction "mismatch". Myocardial stunning was first described in laboratory canine experiments in the 1970s where LV wall abnormalities were observed following coronary artery occlusion and subsequent reperfusion.
Wikidata
Myocardial stunning
In cardiology, stunned myocardium is a state when some section of the myocardium shows a form of contractile abnormality. This is a segmental dysfunction which persists for a variable period of time, about two weeks, even after ischemia has been relieved. In this situation, while myocardial blood flow returns to normal, function is still depressed for a variable period of time. Myocardial stunning is the reversible reduction of function of heart contraction after reperfusion not accounted for by tissue damage or reduced blood flow. After total ischemia occurs, the myocardium switches immediately form aerobic glycolysis to anaerobic glycolysis resulting in the reduced ability to produce high energy phosphates such as ATP and Creatinine Phosphate. At this point, the lack of the energy and lactate accumulation results in cessation of contraction within 60 seconds of ischemia. Subsequent to this is a period of "myocardial stunning," in which reversible ischemic damage is taking place. At approximately 30 minutes after the onset of total ischemia the damage becomes irreversible, thereby ending the phase of myocardial stunning.
U.S. National Library of Medicine
Myocardial Stunning
Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity. It occurs frequently, both in the experimental laboratory and in clinical medicine. Since stunned myocardium occurs adjacent to necrotic tissue after prolonged coronary occlusion, many myocardial infarcts may be a mixture of necrotic and stunned tissue. (Braunwald, Heart Disease, 1992, p1176)
Numerology
Chaldean Numerology
The numerical value of myocardial stunning in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of myocardial stunning in Pythagorean Numerology is: 3
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"myocardial stunning." Definitions.net. STANDS4 LLC, 2024. Web. 30 Apr. 2024. <https://www.definitions.net/definition/myocardial+stunning>.
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