What does mutation mean?

Definitions for mutation
myuˈteɪ ʃənmu·ta·tion

This dictionary definitions page includes all the possible meanings, example usage and translations of the word mutation.

Princeton's WordNet

  1. mutant, mutation, variation, sportnoun

    (biology) an organism that has characteristics resulting from chromosomal alteration

  2. mutation, genetic mutation, chromosomal mutationnoun

    (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism

  3. mutationnoun

    a change or alteration in form or qualities

GCIDE

  1. mutationnoun

    (Biol.) (a) As now employed (first by de Vries), a cellular process resulting in a sudden inheritable variation (the offspring differing from its parents in some well-marked character or characters) as distinguished from a gradual variation in which the new characters become fully developed only in the course of many generations. The occurrence of mutations, the selection of strains carrying mutations permitting enhanced survival under prevailing conditions, and the mechanism of hereditary of the characters so appearing, are well-established facts; whether and to what extent the mutation process has played the most important part in the evolution of the existing species and other groups of organisms is an unresolved question. (b) The result of the above process; a suddenly produced variation. Mutations can occur by a change in the fundamental coding sequence of the hereditary material, which in most organisms is DNA, but in some viruses is RNA. It can also occur by rearrangement of an organism's chromosomes. Specific mutations due to a change in DNA sequence have been recognized as causing certain specific hereditary diseases. Certain processes which produce variation in the genotype of an organism, such as sexual mixing of chromosomes in offspring, or artificially induced recombination or introduction of novel genetic material into an organism, are not referred to as mutation.

Wiktionary

  1. mutationnoun

    any alteration or change

  2. mutationnoun

    Any heritable change of the base-pair sequence of genetic material

  3. mutationnoun

    a mutant

Samuel Johnson's Dictionary

  1. Mutationnoun

    Change; alteration.

    Etymology: mutation, French; mutatio, Lat.

    His honour
    Was nothing but mutation, ay, and that
    From one bad thing to worse. William Shakespeare, Cymbeline.

    The vicissitude or mutations in the superior globe are no fit matter for this present argument. Francis Bacon, Essays.

    To make plants grow out of the sun or open air is a great mutation in nature, and may induce a change in the seed. Francis Bacon.

Wikipedia

  1. Mutation

    In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements.Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source of all genetic variation, providing the raw material on which evolutionary forces such as natural selection can act. Mutation can result in many different types of change in sequences. Mutations in genes can have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in non-genic regions. A 2007 study on genetic variations between different species of Drosophila suggested that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70% of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or marginally beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.

ChatGPT

  1. mutation

    A mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. These changes can occur in a single DNA building block or large segments of chromosomes. They can lead to variations among species, enable evolution, cause diseases and conditions, or have no significant effect. Mutations can occur spontaneously or as a result of exposure to specific environmental factors.

Webster Dictionary

  1. Mutationnoun

    change; alteration, either in form or qualities

  2. Etymology: [L. mutatio, fr. mutare to change: cf. F. mutation. See Mutable.]

Wikidata

  1. Mutation

    In genetics, a mutation is a change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to DNA or to RNA genomes, from errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements. Mutations may or may not produce discernable changes in the observable characteristics of an organism. Mutations play a part in both normal and abnormal biological processes, including evolution, cancer, and the development of the immune system. Mutation can result in several different types of change in sequences, Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions. One study on genetic variations between different species of Drosophila suggests that if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms having damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations.

U.S. National Library of Medicine

  1. Mutation

    Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

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Numerology

  1. Chaldean Numerology

    The numerical value of mutation in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of mutation in Pythagorean Numerology is: 5

Examples of mutation in a Sentence

  1. George Dimopoulos:

    The problem is that these GM mutants have a fitness cost, current studies are addressing this issue, trying to find ways of making these mosquitoes as competitive as the wild type. One way of perhaps doing this is to inactivate the parasite-host factor, FREP1, in the adult female gut only, as opposed to the entire mosquito at all developmental stages. One can also integrate our strategy with a so-called gene-drive to more effectively drive the mutation into a mosquito population.

  2. Simon Clarke:

    When a virus is swilling around the population, it can mutate, every time it replicates( infects) there is the possibility of a mutation. While most of those are neutral or even damage the virus, every so often a mutation gives the virus a' fitness advantage,' which makes it more transmissible. Bluntly, the more people with a second dose, the less this thing can mutate in dangerous ways.

  3. Prime Minister Igor Matovic:

    We are in a very tough situation... There is no country in Europe with a higher documented proportion of the British mutation.

  4. Rice University:

    Evolution is faster or slower depending on how much of an advantage there is to having a certain mutation, if a mutation pops up for people living on Mars, and it gives them a 50-percent survival advantage, thats ahugeadvantage, right? And that means that those individuals are going to be passing those genes on at a much higher rate than they otherwise would have.

  5. Anthony Fauci:

    We need to keep the levels of virus to the lowest possible level, and that is our best defense. If a virus is not very robustly replicating and spreading, it gives it less of a chance of a mutation, which gives it less of a chance of the evolving of another variant.

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Translations for mutation

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"mutation." Definitions.net. STANDS4 LLC, 2024. Web. 27 Apr. 2024. <https://www.definitions.net/definition/mutation>.

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