What does mevastatin mean?
Definitions for mevastatin
mev·as·tatin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word mevastatin.
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Wiktionary
mevastatinnoun
A statin, produced by the mould Penicillium citrinum, used in the production of pravastatin
Wikipedia
Mevastatin
Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class. It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s, and he identified it as a HMG-CoA reductase inhibitor, i.e., a statin. Mevastatin might be considered the first statin drug; clinical trials on mevastatin were performed in the late 1970s in Japan, but it was never marketed. The first statin drug available to the general public was lovastatin. Mevastatin has since been derivatized to the compound pravastatin, which is a pharmaceutical used in the lowering of cholesterol and preventing cardiovascular disease. In vitro, it has antiproliferative properties.A British group isolated the same compound from Penicillium brevicompactum, named it compactin, and published their results in 1976. The British group mentions antifungal properties with no mention of HMG-CoA reductase inhibition. High doses inhibit growth and proliferation of melanoma cells.
Wikidata
Mevastatin
Mevastatin, compactin, ML-236B is a hypolipidemic agent that belongs to the statins class. It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s and he identified it as a HMG-CoA reductase inhibitor, i.e.; a statin. Mevastatin might be considered the first statin drug, but, although clinical trials on mevastatin were performed in the late 1970s in Japan, it was never marketed.The first statin drug available to the general public was lovastatin. In vitro it has antiproliferative properties. A British group isolated the same compound from Penicillium brevicompactum, named it compactin and also published it in 1976. The British group mentions anti-fungal properties with no mention of HMG-CoA Reductase inhibition. High doses inhibit growth and proliferation of melanoma cells.
Numerology
Chaldean Numerology
The numerical value of mevastatin in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of mevastatin in Pythagorean Numerology is: 7
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"mevastatin." Definitions.net. STANDS4 LLC, 2025. Web. 20 Jan. 2025. <https://www.definitions.net/definition/mevastatin>.
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