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  1. Losartan

    Losartan, sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys. Besides hypertension, it is also used in diabetic kidney disease, heart failure, and left ventricular enlargement. It comes as a tablet that is taken by mouth. It may be used alone or in addition to other blood pressure medication. Up to six weeks may be required for the full effects to occur.Common adverse effects include muscle cramps, stuffy nose, cough, high blood potassium, and anemia. Severe adverse effects may include angioedema, low blood pressure, and kidney problems. Use during pregnancy may result in harm to the baby. Use is not recommended during breastfeeding. It works by blocking angiotensin II.Losartan was patented in 1986, and approved for medical use in the United States in 1995. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the ninth most commonly prescribed medication in the United States, with more than 54 million prescriptions. A version combined with hydrochlorothiazide is available which, in 2020, was the 93rd most commonly prescribed medication in the United States, with more than 7 million prescriptions.


  1. Losartan

    Losartan is an angiotensin II receptor antagonist drug used mainly to treat high blood pressure. Losartan was the first angiotensin II receptor antagonist to be marketed. Losartan potassium is marketed by Merck & Co. Inc. under the trade name Cozaar. As of 2009, In south east Asia Losartan potassium is marketed by Delta Pharma Ltd. under the trade name Anin. losartan is available in generic form. As with all angiotensin II type 1 receptor antagonists, losartan is indicated for the treatment of hypertension. It may also delay progression of diabetic nephropathy, and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria or proteinuria. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most patients, an angiotensin II receptor antagonist such as losartan is recommended as first-line treatment in patients under the age of 55 who cannot tolerate an ACE inhibitor. The LIFE study demonstrated losartan was significantly superior to atenolol in the primary prevention of adverse cardiovascular events, with a significant reduction in cardiovascular morbidity and mortality for a comparable reduction in blood pressure. A study hints that losartan has a beneficial effect on mitochondria by reversing age related dysfunction in maintaining normal blood pressure and cellular energy usage. The maximal effects on blood pressure usually occur within 3–6 weeks upon starting losartan.

U.S. National Library of Medicine

  1. Losartan

    An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.

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  1. Chaldean Numerology

    The numerical value of losartan in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of losartan in Pythagorean Numerology is: 1

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"losartan." Definitions.net. STANDS4 LLC, 2024. Web. 23 May 2024. <https://www.definitions.net/definition/losartan>.

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