What does importin mean?

Definitions for importin
im·portin

This dictionary definitions page includes all the possible meanings, example usage and translations of the word importin.


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Wiktionary

  1. importinnoun

    Any of various karyopherins that move other protein molecules into the cell nucleus by binding to a specific recognition sequence.

Wikipedia

  1. Importin

    Importin is a type of karyopherin that transports protein molecules from the cell's cytoplasm to the nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin α and importin β. Members of the importin-β family can bind and transport cargo by themselves, or can form heterodimers with importin-α. As part of a heterodimer, importin-β mediates interactions with the pore complex, while importin-α acts as an adaptor protein to bind the nuclear localization signal (NLS) on the cargo. The NLS-Importin α-Importin β trimer dissociates after binding to Ran GTP inside the nucleus, with the two importin proteins being recycled to the cytoplasm for further use.

Wikidata

  1. Importin

    Importin is a type of protein that moves other protein molecules into the nucleus by binding to a specific recognition sequence, called the nuclear localization signal. Importin is classified as a karyopherin. Importin has two subunits, importin α and importin β. Members of the importin-beta family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal on the cargo through the classical NLS import of proteins. The NLS-Importin α-Importin β trimer dissociates after binding to Ran GTP inside the nucleus. Proteins can contain one or two NLS motifs. Importin-alpha contains several armadillo repeats, which produce a curving structure with two NLS-binding sites, a major one close to the N terminus and a minor one close to the C terminus. Importin alpha also contains an N-terminal importin beta binding domain that contains an auto-regulatory region. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins, which is important for importin-beta mediated transport.

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Numerology

  1. Chaldean Numerology

    The numerical value of importin in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of importin in Pythagorean Numerology is: 6

Popularity rank by frequency of use

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"importin." Definitions.net. STANDS4 LLC, 2024. Web. 14 Apr. 2024. <https://www.definitions.net/definition/importin>.

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