Definitions for importin
im·portin

WiktionaryRate this definition:0.0 / 0 votes

1. importinnoun

   Any of various karyopherins that move other protein molecules into the cell nucleus by binding to a specific recognition sequence.

WikipediaRate this definition:0.0 / 0 votes

1. Importin

   Importin is a type of karyopherin that transports protein molecules from the cell's cytoplasm to the nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin α and importin β. Members of the importin-β family can bind and transport cargo by themselves, or can form heterodimers with importin-α. As part of a heterodimer, importin-β mediates interactions with the pore complex, while importin-α acts as an adaptor protein to bind the nuclear localization signal (NLS) on the cargo. The NLS-Importin α-Importin β trimer dissociates after binding to Ran GTP inside the nucleus, with the two importin proteins being recycled to the cytoplasm for further use.

WikidataRate this definition:0.0 / 0 votes

1. Importin

   Importin is a type of protein that moves other protein molecules into the nucleus by binding to a specific recognition sequence, called the nuclear localization signal. Importin is classified as a karyopherin. Importin has two subunits, importin α and importin β. Members of the importin-beta family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal on the cargo through the classical NLS import of proteins. The NLS-Importin α-Importin β trimer dissociates after binding to Ran GTP inside the nucleus. Proteins can contain one or two NLS motifs. Importin-alpha contains several armadillo repeats, which produce a curving structure with two NLS-binding sites, a major one close to the N terminus and a minor one close to the C terminus. Importin alpha also contains an N-terminal importin beta binding domain that contains an auto-regulatory region. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins, which is important for importin-beta mediated transport.

How to pronounce importin?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say importin in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of importin in Chaldean Numerology is: 5

2. Pythagorean Numerology

   The numerical value of importin in Pythagorean Numerology is: 6

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Importin
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Importin
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=importin