Definitions for hydromorphone hydrochloride
hy·dro·mor·phone hy·drochlo·ride

Princeton's WordNetRate this definition:0.0 / 0 votes

1. hydromorphone hydrochloride, hydromorphone, Dilaudidnoun

   a narcotic analgesic (trade name Dilaudid) used to treat moderate to severe pain

WikipediaRate this definition:0.0 / 0 votes

1. hydromorphone hydrochloride

   Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is an opioid used to treat moderate to severe pain. Typically, long-term use is only recommended for pain due to cancer. It may be used by mouth or by injection into a vein, muscle, or under the skin. Effects generally begin within half an hour and last for up to five hours.Common side effects include dizziness, sleepiness, nausea, itchiness, and constipation. Serious side effects may include abuse, low blood pressure, seizures, respiratory depression, and serotonin syndrome. Rapidly decreasing the dose may result in opioid withdrawal. Generally, use during pregnancy or breastfeeding is not recommended. Hydromorphone is believed to work by activating opioid receptors, mainly in the brain and spinal cord. Hydromorphone 2 mg IV is equivalent to approximately 10 mg morphine IV.Hydromorphone was patented in 1923. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 250th most commonly prescribed medication in the United States, with more than 1 million prescriptions. Hydromorphone is made from morphine.

ChatGPTRate this definition:0.0 / 0 votes

1. hydromorphone hydrochloride

   Hydromorphone hydrochloride is a highly potent synthetic opioid analgesic medication used primarily in the treatment of severe pain. It's sometimes prescribed for individuals who require continuous, around-the-clock pain relief and who cannot be treated with other medications. It's available in tablet and liquid form, and it works by altering the way the brain and nervous system respond to pain. It has a higher fat solubility than morphine, contributing to its higher potency and faster onset of action. In addition, like other opioids, it also has the potential for addiction, abuse, and misuse.

WikidataRate this definition:0.0 / 0 votes

1. Hydromorphone Hydrochloride

   The hydrochloride salt form of hydromorphone, the hydrogenated ketone of morphine, a semi-synthetic opioid with analgesic effects. Hydromorphone selectively binds the mu-opioid receptor which is linked through G-proteins. Binding stimulates the exchange of guanosine triphosphate (GTP) for guanosine diphosphate (GDP) on the G-protein complex and interacts with and inhibits adenylate cyclase located at the inner surface of the plasma membrane. This leads to a reduction in intracellular cyclic 3',5'-adenosine monophosphate (cAMP). Further, voltage-gated potassium channels are activated, thereby causing hyperpolarization and reducing neuronal excitability. In addition, the opening of voltage-gated calcium channels is inhibited, thereby leading to an inhibition of calcium entry and a reduction in the release of various neurotransmitters, including GABA, vasopressin, somatostatin, insulin and glucagons.

Matched Categories

1. • Analgesic

How to pronounce hydromorphone hydrochloride?

1. Alex

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   British

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How to say hydromorphone hydrochloride in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of hydromorphone hydrochloride in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of hydromorphone hydrochloride in Pythagorean Numerology is: 3

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=hydromorphone hydrochloride
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Hydromorphone_Hydrochloride
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=hydromorphone hydrochloride