Definitions for hybridoma
ˌhaɪ brɪˈdoʊ məhy·brido·ma

Princeton's WordNetRate this definition:0.0 / 0 votes

1. hybridomanoun

   a hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibody

WiktionaryRate this definition:0.0 / 0 votes

1. hybridomanoun

   A hybrid cell engineered from a lymphocyte and a tumour cell; used to generate monoclonal antibodies

WikipediaRate this definition:0.0 / 0 votes

1. hybridoma

   Hybridoma technology is a method for producing large numbers of identical antibodies (also called monoclonal antibodies). This process starts by injecting a mouse (or other mammal) with an antigen that provokes an immune response. A type of white blood cell, the B cell, produces antibodies that bind to the injected antigen. These antibody producing B-cells are then harvested from the mouse and, in turn, fused with immortal B cell cancer cells, a myeloma, to produce a hybrid cell line called a hybridoma, which has both the antibody-producing ability of the B-cell and the longevity and reproductivity of the myeloma. The hybridomas can be grown in culture, each culture starting with one viable hybridoma cell, producing cultures each of which consists of genetically identical hybridomas which produce one antibody per culture (monoclonal) rather than mixtures of different antibodies (polyclonal). The myeloma cell line that is used in this process is selected for its ability to grow in tissue culture and for an absence of antibody synthesis. In contrast to polyclonal antibodies, which are mixtures of many different antibody molecules, the monoclonal antibodies produced by each hybridoma line are all chemically identical. The production of monoclonal antibodies was invented by César Milstein and Georges J. F. Köhler in 1975. They shared the Nobel Prize of 1984 for Medicine and Physiology with Niels Kaj Jerne, who made other contributions to immunology. The term hybridoma was coined by Leonard Herzenberg during his sabbatical in César Milstein's laboratory in 1976–1977.

ChatGPTRate this definition:0.0 / 0 votes

1. hybridoma

   A hybridoma is a type of cell that is produced through the fusion of a specific antibody-producing B cell with a myeloma (cancer) cell. This technique, developed in the 1970s, allows for the mass production of specific antibodies, also known as monoclonal antibodies, for use in research, diagnostics and therapeutics. The hybridoma cells have the ability to replicate indefinitely while maintaining the capacity to produce antibodies.

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1. • Somatic Cell

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Numerology

1. Chaldean Numerology

   The numerical value of hybridoma in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of hybridoma in Pythagorean Numerology is: 5

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=hybridoma
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Hybridoma
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Hybridoma
4. ^ ChatGPT
   https://chat.openai.com