What does hepatoxicity mean?
Definitions for hepatoxicity
hep·a·tox·i·c·i·ty
This dictionary definitions page includes all the possible meanings, example usage and translations of the word hepatoxicity.
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Wiktionary
hepatoxicitynoun
toxicity that affects the liver
Wikipedia
hepatoxicity
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses (e.g. paracetamol) and sometimes even when introduced within therapeutic ranges (e.g. halothane), may injure the organ. Other chemical agents, such as those used in laboratories and industries, natural chemicals (e.g., microcystins), and herbal remedies (two prominent examples being kava, mechanism unknown, and comfrey, through its pyrrolizidine alkaloid content) can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins. More than 900 drugs have been implicated in causing liver injury (see LiverTox, external link, below) and it is the most common reason for a drug to be withdrawn from the market. Hepatotoxicity and drug-induced liver injury also account for a substantial number of compound failures, highlighting the need for toxicity prediction models (e.g. DTI), and drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development process. Chemicals often cause subclinical injury to the liver, which manifests only as abnormal liver enzyme tests. Drug-induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.
ChatGPT
hepatoxicity
Hepatotoxicity is the ability of a substance to cause damage or harm to the liver. This can occur due to the direct toxic effects of a substance on liver cells, or as a result of the body metabolizing the substance into a toxic compound that harms the liver. Hepatotoxicity can lead to liver inflammation, injury, and dysfunction, and can be a serious and potentially life-threatening condition.
Numerology
Chaldean Numerology
The numerical value of hepatoxicity in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of hepatoxicity in Pythagorean Numerology is: 2
Translations for hepatoxicity
From our Multilingual Translation Dictionary
- 肝毒性Chinese
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"hepatoxicity." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/hepatoxicity>.
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