What does hamartoma mean?

Definitions for hamartoma

This dictionary definitions page includes all the possible meanings, example usage and translations of the word hamartoma.

Princeton's WordNet

  1. hamartomanoun

    a focal growth that resembles a neoplasm but results from faulty development in an organ


  1. hamartomanoun

    A benign mass of disorganized tissue.


  1. Hamartoma

    A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (monoclonality), as would typically define a benign neoplasm/tumor. Despite this, many hamartomas are found to have clonal chromosomal aberrations that are acquired through somatic mutations, and on this basis the term hamartoma is sometimes considered synonymous with neoplasm. Hamartomas are by definition benign, slow-growing or self-limiting, though the underlying condition may still predispose the individual towards malignancies. Hamartomas are usually caused by a genetic syndrome that affects the development cycle of all or at least multiple cells. Many of these conditions are classified as overgrowth syndromes or cancer syndromes. Hamartomas occur in many different parts of the body and are most often asymptomatic incidentalomas (undetected until they are found incidentally on an imaging study obtained for another reason). Additionally, the definition of hamartoma versus benign neoplasm is often unclear, since both lesions can be clonal. Lesions such as adenomas, developmental cysts, hemangiomas, lymphangiomas and rhabdomyomas within the kidneys, lungs or pancreas are interpreted by some experts as hamartomas while others consider them true neoplasms. Moreover, even though hamartomas show a benign histology, there is a risk of some rare but life-threatening complications such as those found in neurofibromatosis type I and tuberous sclerosis.It is different from choristoma, a closely related form of heterotopia. The two can be differentiated as follows: a hamartoma is an excess of normal tissue in a normal situation (e.g., a birthmark on the skin), while a choristoma is an excess of tissue in an abnormal situation (e.g., pancreatic tissue in the duodenum). The term hamartoma is from the Greek ἁμαρτία, hamartia ("error"), and was introduced by D.P.G. Albrecht in 1904.


  1. hamartoma

    A hamartoma is a benign, noncancerous tumor that consists of an abnormal mixture of cells and tissues normally found in the area of the body where the tumor grows. Although they grow, they do not spread to other parts of the body like cancerous tumors. Hamartomas can occur in various parts of the body including the lungs, liver, kidneys, heart, and brain. They are typically present at birth or develop within a few years thereafter.


  1. Hamartoma

    A hamartoma is a benign, focal malformation that resembles a neoplasm in the tissue of its origin. This is not a malignant tumor, and it grows at the same rate as the surrounding tissues. It is composed of tissue elements normally found at that site, but which are growing in a disorganized mass. They occur in many different parts of the body and are most often asymptomatic and undetected unless seen on an image taken for another reason. Choristomas, forms of heterotopia, are closely related benign tumors. These tumors also contain normal tissues but are found in abnormal locations.

U.S. National Library of Medicine

  1. Hamartoma

    A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.

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  1. Chaldean Numerology

    The numerical value of hamartoma in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of hamartoma in Pythagorean Numerology is: 9

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"hamartoma." Definitions.net. STANDS4 LLC, 2024. Web. 29 Feb. 2024. <https://www.definitions.net/definition/hamartoma>.

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