Definitions for glioblastoma
glioblas·tom·a

Princeton's WordNetRate this definition:0.0 / 0 votes

1. glioblastoma, spongioblastomanoun

   a fast-growing malignant brain tumor composed of spongioblasts; nearly always fatal

WiktionaryRate this definition:0.0 / 0 votes

1. glioblastomanoun

   A fast-growing, malignant tumor of the brain

WikipediaRate this definition:0.0 / 0 votes

1. Glioblastoma

   Glioblastoma, previously known as glioblastoma multiforme (GBM), is one of the most aggressive types of cancer that begin within the brain. Initially, signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke. Symptoms often worsen rapidly and may progress to unconsciousness.The cause of most cases of glioblastoma is not known. Uncommon risk factors include genetic disorders, such as neurofibromatosis and Li–Fraumeni syndrome, and previous radiation therapy. Glioblastomas represent 15% of all brain tumors. They can either start from normal brain cells or develop from an existing low-grade astrocytoma. The diagnosis typically is made by a combination of a CT scan, MRI scan, and tissue biopsy.There is no known method of preventing the cancer. Treatment usually involves surgery, after which chemotherapy and radiation therapy are used. The medication temozolomide is frequently used as part of chemotherapy. High-dose steroids may be used to help reduce swelling and decrease symptoms. Surgical removal (decompression) of the tumor is linked to increased survival, but only by some months.Despite maximum treatment, the cancer almost always recurs. The typical duration of survival following diagnosis is 10–13 months, with fewer than 5–10% of people surviving longer than five years. Without treatment, survival is typically three months. It is the most common cancer that begins within the brain and the second-most common brain tumor, after meningioma. About 3 in 100,000 people develop the disease per year. The average age at diagnosis is 64, and the disease occurs more commonly in males than females.

ChatGPTRate this definition:0.0 / 0 votes

1. glioblastoma

   Glioblastoma, also known as glioblastoma multiforme, is a fast-growing, aggressive type of central nervous system tumor that forms on the supportive tissue of the brain. It's the most common type of malignant brain tumor in adults and can occur at any age but tends to occur more often in older adults. Glioblastoma can cause rapidly worsening symptoms including headaches, nausea, personality changes, and seizures. Treatment typically involves surgery, radiation, and chemotherapy, but despite aggressive treatment, glioblastomas often recur and survival rates are generally low.

WikidataRate this definition:0.0 / 0 votes

1. Glioblastoma

   Glioblastoma is the most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma). Two histologic variants are recognized: giant cell glioblastoma and gliosarcoma.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Glioblastoma

   A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Matched Categories

1. • Brain Tumor

How to pronounce glioblastoma?

1. Alex

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How to say glioblastoma in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of glioblastoma in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of glioblastoma in Pythagorean Numerology is: 9

Examples of glioblastoma in a Sentence

1. Jonathan Simons:

   For now, we see no active surveillance for colon or pancreatic cancer or glioblastoma, but we know that follicular lymphoma, a low-growing, low-grade cancer, does overlap with nonaggressive prostate cancer.

2. Manmeet Ahluwalia:

   There is a great deal of excitement about some of the immunotherapy-based approaches in treatment of glioblastoma, immunotherapy has been shown to be promising in a number of other cancers, like lung cancer and melanoma. We are currently evaluating a number of such approaches. The ones which are most furthest along are some trials that are evaluating nivolumab, which is an anti-PD1 therapy in combination with chemotherapy and radiation.

3. Erin Dunbar:

   This is an unbelievably tender topic to talk about with our patients because when someone is diagnosed with a glioblastoma, it is a tremendous left turn in their life. They have been told they have a highly aggressive, incurable tumor that will undoubtedly shorten their life, barring a miracle.

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=glioblastoma
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Glioblastoma
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Glioblastoma
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=glioblastoma