Definitions for g protein
g protein

WiktionaryRate this definition:0.0 / 0 votes

1. G proteinnoun

   Any of a class of proteins, found in cell membranes, that pass signals between hormone receptors and effector enzymes

2. Etymology: *guanine nucleotide binding protein

WikipediaRate this definition:0.0 / 0 votes

1. G protein

   G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior. Their activity is regulated by factors that control their ability to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). When they are bound to GTP, they are 'on', and, when they are bound to GDP, they are 'off'. G proteins belong to the larger group of enzymes called GTPases. There are two classes of G proteins. The first function as monomeric small GTPases (small G-proteins), while the second function as heterotrimeric G protein complexes. The latter class of complexes is made up of alpha (α), beta (β) and gamma (γ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex .Heterotrimeric G proteins located within the cell are activated by G protein-coupled receptors (GPCRs) that span the cell membrane. Signaling molecules bind to a domain of the GPCR located outside the cell, and an intracellular GPCR domain then in turn activates a particular G protein. Some active-state GPCRs have also been shown to be "pre-coupled" with G proteins, whereas in other cases a collision coupling mechanism is thought to occur. The G protein activates a cascade of further signaling events that finally results in a change in cell function. G protein-coupled receptor and G proteins working together transmit signals from many hormones, neurotransmitters, and other signaling factors. G proteins regulate metabolic enzymes, ion channels, transporter proteins, and other parts of the cell machinery, controlling transcription, motility, contractility, and secretion, which in turn regulate diverse systemic functions such as embryonic development, learning and memory, and homeostasis.

WikidataRate this definition:0.0 / 0 votes

1. G protein

   G proteins, also known as guanosine nucleotide-binding proteins, are a family of proteins involved in transmitting signals from a variety of different stimuli outside a cell into the inside of the cell. G proteins function as molecular switches. Their activity is regulated by factors that control their ability to bind to and hydrolyze guanosine triphosphate to guanosine diphosphate. When they bind GTP, they are 'on', and, when they bind GDP, they are 'off'. G proteins belong to the larger group of enzymes called GTPases. There are two classes of G proteins. The first function as monomeric small GTPases while the second form and function as heterotrimeric G protein complexes. The latter class of complexes are made up of alpha, beta and gamma subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex. G proteins located within the cell are activated by G protein-coupled receptors that span the cell membrane. Signaling molecules bind to a domain of the GPCR located outside the cell. An intracellular GPCR domain in turn activates a G protein. The G protein activates a cascade of further signaling events that finally results in a change in cell function. G protein-coupled receptor and G proteins working together transmit signals from many hormones, neurotransmitters, and other signaling factors. G proteins regulate metabolic enzymes, ion channels, transporter, and other parts of the cell machinery, controlling transcription, motility, contractility, and secretion, which in turn regulate diverse systemic functions such as embryonic development, learning and memory, and homeostasis.

How to pronounce g protein?

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How to say g protein in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of g protein in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of g protein in Pythagorean Numerology is: 5

Examples of g protein in a Sentence

1. Valter Longo:

   The lower or lack of association between red meat intake and mortality in other countries or areas of the world indicates that red meat may contribute to mortality in the United States by providing a high protein content but also because it may contain other factors that contribute to damage.

2. Sara Peternell:

   They may even potentially develop some food intolerances because their gut is just not prepared yet for some of the protein components in that particular food.

3. Randi Hagerman:

   The lack of the Fragile X protein FMRP actually deregulates a number of systems in the brain, when FMRP is missing, many other genes produce way too much protein from their specific genes, and so that actually interferes with normal development.

4. Stanley Erck:

   We have heard in today's VRBPAC meeting the significant support for our vaccine from physicians, healthcare organizations, and consumers who are eagerly anticipating a protein-based vaccine option.

5. Alissa Rumsey:

   Not only does protein stay in Maggie Moon stomach and promote feelings of fullness, it's been shown to have an appetite-suppressing effect.

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/G_Protein
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/G_Protein
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=g protein