What does ferroptosis mean?
Definitions for ferroptosis
fer·rop·to·sis
This dictionary definitions page includes all the possible meanings, example usage and translations of the word ferroptosis.
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Wikipedia
Ferroptosis
Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis. Ferroptosis is initiated by the failure of the glutathione-dependent antioxidant defenses, resulting in unchecked lipid peroxidation and eventual cell death. Lipophilic antioxidants and iron chelators can prevent ferroptotic cell death. Although the connection between iron and lipid peroxidation has been appreciated for years, it was not until 2012 that Brent Stockwell and Scott Dixon coined the term ferroptosis and described several of its key features.Researchers have identified roles in which ferroptosis can contribute to the medical field such as in aiding in cancer treatments where this form of cell death can be induced in the human body. Ferroptosis activation plays a regulatory role on growth of tumor cells in the human body. However, the positive effects of ferroptosis could be potentially neutralized by its disruption of metabolic pathways and disruption of homeostasis in the human body. Since ferroptosis is a form of regulated cell death, some of the molecules that regulate ferroptosis are involved in metabolic pathways that regulate cysteine exploitation, glutathione state, nicotinamide adenine dinucleotide phosphate function, lipid peroxidation and iron homeostasis.
Numerology
Chaldean Numerology
The numerical value of ferroptosis in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of ferroptosis in Pythagorean Numerology is: 7
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"ferroptosis." Definitions.net. STANDS4 LLC, 2024. Web. 13 Sep. 2024. <https://www.definitions.net/definition/ferroptosis>.
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