What does f2-isoprostanes mean?
Definitions for f2-isoprostanes
f2-isoprostanes
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Wikipedia
f2-isoprostanes
The isoprostanes are prostaglandin-like compounds formed in vivo from the free radical-catalyzed peroxidation of essential fatty acids (primarily arachidonic acid) without the direct action of cyclooxygenase (COX) enzymes. The compounds were discovered in 1990 by L. Jackson Roberts and Jason D. Morrow in the Division of Clinical Pharmacology at Vanderbilt University. These nonclassical eicosanoids possess potent biological activity as inflammatory mediators that augment the perception of pain. These compounds are accurate markers of lipid peroxidation in both animal and human models of oxidative stress. Elevated levels of isoprostanes are suspected of contributing to increased risk of heart attack in patients taking Coxibs. Isoprostanes and their metabolites have also been shown to be elevated in the urine of cigarette smokers, and have been suggested as biomarkers of oxidative stress in smokers.
U.S. National Library of Medicine
F2-Isoprostanes
Isoprostanes derived from the free radical oxidation of ARACHIDONIC ACID. Although similar in structure to enzymatically synthesized prostaglandin F2alpha (DINOPROST), they occur through non-enzymatic oxidation of cell membrane lipids.
Numerology
Chaldean Numerology
The numerical value of f2-isoprostanes in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of f2-isoprostanes in Pythagorean Numerology is: 5
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"f2-isoprostanes." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/f2-isoprostanes>.
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