What does extrapyramidal symptoms mean?
Definitions for extrapyramidal symptoms
ex·trapyra·mi·dal symp·toms
This dictionary definitions page includes all the possible meanings, example usage and translations of the word extrapyramidal symptoms.
Wikipedia
Extrapyramidal symptoms
Extrapyramidal symptoms (EPS) are symptoms that are archetypically associated with the extrapyramidal system of the brain's cerebral cortex. When such symptoms are caused by medications or other drugs, they are also known as extrapyramidal side effects (EPSE). The symptoms can be acute (short-term) or chronic (long-term). They include movement dysfunction such as dystonia (continuous spasms and muscle contractions), akathisia (may manifest as motor restlessness), parkinsonism characteristic symptoms such as rigidity, bradykinesia (slowness of movement), tremor, and tardive dyskinesia (irregular, jerky movements). Extrapyramidal symptoms are a reason why subjects drop out of clinical trials of antipsychotics; of the 213 (14.6%) subjects that dropped out of one of the largest clinical trials of antipsychotics (the CATIE trial (Clinical Antipsychotic Trials for Intervention Effectiveness), which included 1460 randomized subjects), 58 (27.2%) of those discontinuations were due to EPS.
Wikidata
Extrapyramidal symptoms
The extrapyramidal system can be affected in a number of ways, which are revealed in a range of extrapyramidal symptoms, also known as extrapyramidal side-effects, such as akinesia and akathisia. Extrapyramidal symptoms are various movement disorders such as acute dystonic reactions, pseudoparkinsonism, Tardive dyskinesia or akathisia suffered as a result of taking dopamine antagonists, usually antipsychotic drugs, which are often used to control psychosis. It can also be a symptom of a metabolic disease. Extrapyramidal syndrome is due to the blockade of dopamine receptors in the basal ganglia, leading to Parkinson-like symptoms such as slow movement, stiffness, and tremor. The Simpson-Angus Scale and the Barnes Akathisia Rating Scale are used to measure extrapyramidal symptoms. Extrapyramidal symptoms are also usually present in patients with neuroleptic malignant syndrome.
Numerology
Chaldean Numerology
The numerical value of extrapyramidal symptoms in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of extrapyramidal symptoms in Pythagorean Numerology is: 1
Translations for extrapyramidal symptoms
From our Multilingual Translation Dictionary
- ekstrapramidal semptomlarTurkish
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"extrapyramidal symptoms." Definitions.net. STANDS4 LLC, 2024. Web. 14 May 2024. <https://www.definitions.net/definition/extrapyramidal+symptoms>.
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