What does excitation–contraction coupling mean?

Definitions for excitation–contraction coupling
ex·ci·ta·tion–·con·trac·tion cou·pling

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Wikidata

  1. Excitation–contraction coupling

    Excitation–contraction coupling is a term coined in 1952 to describe the physiological process of converting an electrical stimulus to a mechanical response. This process is fundamental to muscle physiology, whereby the electrical stimulus is usually an action potential and the mechanical response is contraction. EC coupling can be dysregulated in many diseases. Though EC coupling has been known for over half a century, it is still an active area of biomedical research. The general scheme is that an action potential arrives to depolarize the cell membrane. By mechanisms specific to the muscle type, this depolarization results in an increase in cytosolic calcium that is called a calcium transient. This increase in calcium activates calcium-sensitive contractile proteins that then use ATP to cause cell shortening.

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Numerology

  1. Chaldean Numerology

    The numerical value of excitation–contraction coupling in Chaldean Numerology is: 6

  2. Pythagorean Numerology

    The numerical value of excitation–contraction coupling in Pythagorean Numerology is: 7

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"excitation–contraction coupling." Definitions.net. STANDS4 LLC, 2024. Web. 21 May 2024. <https://www.definitions.net/definition/excitation%E2%80%93contraction+coupling>.

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