Definitions for estradiol
ˌɛs trəˈdaɪ ɔl, -ɒlestra·di·ol

Princeton's WordNetRate this definition:0.0 / 0 votes

1. estradiol, oestradiolnoun

   the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer

WiktionaryRate this definition:0.0 / 0 votes

1. estradiolnoun

   A potent estrogenic hormone ((17)-estra-1,3,5-triene-3,17-diol) produced in the ovaries of all vertebrates; the synthetic compound is used medicinally to treat estrogen deficiency and breast cancer.

WikipediaRate this definition:0.0 / 0 votes

1. Estradiol

   Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower than in females, estradiol has important roles in males as well. Apart from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species.Estradiol is produced especially within the follicles of the ovaries, but also in other tissues including the testicles, the adrenal glands, fat, liver, the breasts, and the brain. Estradiol is produced in the body from cholesterol through a series of reactions and intermediates. The major pathway involves the formation of androstenedione, which is then converted by aromatase into estrone and is subsequently converted into estradiol. Alternatively, androstenedione can be converted into testosterone, which can then be converted into estradiol. Upon menopause in females, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels. In addition to its role as a natural hormone, estradiol is used as a medication, for instance in menopausal hormone therapy and feminizing hormone therapy for transgender women; for information on estradiol as a medication, see the estradiol (medication) article.

ChatGPTRate this definition:0.0 / 0 votes

1. estradiol

   Estradiol is a form of estrogen, a female sex hormone that’s primarily produced by the ovaries. It plays a crucial role in the regulation of the menstrual cycle and reproductive system, the development of secondary sexual characteristics and maintaining the health of tissues such as those in the heart, bones, and breasts. Levels of estradiol also influence certain aspects of mood and cognitive function. In addition to its natural production in the body, estradiol can be made synthetically for use in hormonal contraception or hormone replacement therapy.

WikidataRate this definition:0.0 / 0 votes

1. Estradiol

   Estradiol is a sex hormone. Estradiol is abbreviated E2 as it has two hydroxyl groups in its molecular structure. Estrone has one and estriol has three. Estradiol is about 10 times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect. Except during the early follicular phase of the menstrual cycle, its serum levels are somewhat higher than that of estrone during the reproductive years of the human female. Thus it is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity. During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulating estrogen in terms of serum levels. Estradiol is also present in males, being produced as an active metabolic product of testosterone. The serum levels of estradiol in males are roughly comparable to those of postmenopausal women. Estradiol in vivo is interconvertible with estrone; estradiol to estrone conversion being favored. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Estradiol

   Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.

Editors ContributionRate this definition:0.0 / 0 votes

1. estradiol

   Is a type of hormone produced and secreted in moderation in the body of an animal or human.

   Estradiol is produced and secreted in both male and females.

   
   

   Submitted by MaryC on June 19, 2020  

Matched Categories

1. • Estrogen

Anagrams for estradiol »

1. steroidal

2. idolaters

3. idolaster

How to pronounce estradiol?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say estradiol in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of estradiol in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of estradiol in Pythagorean Numerology is: 4

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=estradiol
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Estradiol
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Estradiol
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=estradiol