Definitions for epistasis
ɪˈpɪs tə sɪs; -ˌsizepis·ta·sis

Princeton's WordNetRate this definition:0.0 / 0 votes

1. hypostasis, epistasisnoun

   the suppression of a gene by the effect of an unrelated gene

WiktionaryRate this definition:0.0 / 0 votes

1. epistasisnoun

   The modification of the expression of a gene by another unrelated one

WikipediaRate this definition:0.0 / 0 votes

1. Epistasis

   Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears. Epistatic mutations therefore have different effects on their own than when they occur together. Originally, the term epistasis specifically meant that the effect of a gene variant is masked by that of a different gene.The concept of epistasis originated in genetics in 1907 but is now used in biochemistry, computational biology and evolutionary biology. The phenomenon arises due to interactions, either between genes (such as mutations also being needed in regulators of gene expression) or within them (multiple mutations being needed before the gene loses function), leading to non-linear effects. Epistasis has a great influence on the shape of evolutionary landscapes, which leads to profound consequences for evolution and for the evolvability of phenotypic traits.

WikidataRate this definition:3.0 / 1 vote

1. Epistasis

   In genetics, epistasis is a phenomenon in which the expression of one gene depends on the presence of one or more "'modifier genes'." A gene whose phenotype is expressed is called epistatic, while one whose phenotype is altered or suppressed is called hypostatic. If two epistatic genes A and B are mutated, and each mutation by itself produces a unique phenotype but the two mutations together show the same phenotype as the gene A mutation, then gene A is epistatic to gene B. Epistasis can be contrasted with dominance, which is an interaction between alleles at the same gene locus. Epistasis is often studied in relation to Quantitative Trait Loci and polygenic inheritance. In general, the expression of any one allele depends in a complicated way on many other alleles; but, because of the way that the science of population genetics was developed, evolutionary scientists tend to think of epistasis as the exception to the rule. In the first models of natural selection devised in the early 20th century, each gene was considered to make its own characteristic contribution to fitness, against an average background of other genes. Some introductory college courses still teach population genetics this way.

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1. • Organic Process

How to pronounce epistasis?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say epistasis in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of epistasis in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of epistasis in Pythagorean Numerology is: 9

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=epistasis
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Epistasis
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Epistasis
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=epistasis