What does diazepam binding inhibitor mean?
Definitions for diazepam binding inhibitor
di·azepam bind·ing in·hibitor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word diazepam binding inhibitor.
Wikidata
Diazepam binding inhibitor
Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor also mediates the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent synthesis of steroids in the adrenal gland. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have also been described for this gene.
U.S. National Library of Medicine
Diazepam Binding Inhibitor
An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.
Numerology
Chaldean Numerology
The numerical value of diazepam binding inhibitor in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of diazepam binding inhibitor in Pythagorean Numerology is: 4
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"diazepam binding inhibitor." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/diazepam+binding+inhibitor>.
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