What does dephosphorylation mean?

Definitions for dephosphorylation
diˈfɒs fər əˈleɪ ʃənde·phos·pho·ry·la·tion

This dictionary definitions page includes all the possible meanings, example usage and translations of the word dephosphorylation.

Wiktionary

  1. dephosphorylationnoun

    The removal of phosphate groups from a compound, especially from a biological compound

Wikipedia

  1. Dephosphorylation

    In biochemistry, dephosphorylation is the removal of a phosphate (PO43−) group from an organic compound by hydrolysis. It is a reversible post-translational modification. Dephosphorylation and its counterpart, phosphorylation, activate and deactivate enzymes by detaching or attaching phosphoric esters and anhydrides. A notable occurrence of dephosphorylation is the conversion of ATP to ADP and inorganic phosphate. Dephosphorylation employs a type of hydrolytic enzyme, or hydrolase, which cleaves ester bonds. The prominent hydrolase subclass used in dephosphorylation is phosphatase, which removes phosphate groups by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl (-OH) group. The reversible phosphorylation-dephosphorylation reaction occurs in every physiological process, making proper function of protein phosphatases necessary for organism viability. Because protein dephosphorylation is a key process involved in cell signalling, protein phosphatases are implicated in conditions such as cardiac disease, diabetes, and Alzheimer's disease.

Wikidata

  1. Dephosphorylation

    Dephosphorylation is the removal of a phosphate group from an organic compound by hydrolysis. It is a reversible post-translational modification that is coupled to the addition of phosphate groups, or phosphorylation. A highly regulated process, dephosphorylation activates and deactivates enzymes by cleaving phosphoric esters and anhydrides. A notable occurrence of dephosphorylation is the conversion of ATP to ADP and inorganic phosphate. Dephosphorylation employs a type of hydrolytic enzyme, or hydrolase, which cleave ester bonds. The prominent hydrolase subclass used in dephosphorylation is phosphatase. Phosphatase removes phosphate groups by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group. The reversible phosphorylation-dephosphorylation reaction occurs in every physiological process, making proper function of protein phosphases necessary for organism viability. Because protein dephosphorylation is a key process involved in cell signalling, protein phosphatases are implicated in conditions such as cardiac disease, diabetes, and Alzheimer's disease.

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Numerology

  1. Chaldean Numerology

    The numerical value of dephosphorylation in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of dephosphorylation in Pythagorean Numerology is: 4

Popularity rank by frequency of use

dephosphorylation#100000#102379#333333

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"dephosphorylation." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/dephosphorylation>.

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