What does dedifferentiation mean?
Definitions for dedifferentiation
diˌdɪf əˌrɛn ʃiˈeɪ ʃənded·if·fer·en·ti·a·tion
This dictionary definitions page includes all the possible meanings, example usage and translations of the word dedifferentiation.
Princeton's WordNet
dedifferentiationnoun
the loss of specialization in form or function
Wiktionary
dedifferentiationnoun
The loss or reversal of differentiation.
Wikipedia
Dedifferentiation
Dedifferentiation (pronounced dē-ˌdi-fə-ˌren-chē-ˈā-shən) is a transient process by which cells become less specialized and return to an earlier cell state within the same lineage. This suggests an increase in a cell potency, meaning that after dedifferentiation, cells may possess an ability to redifferentiate into more cell types than it did before. This is in contrast to differentiation, where differences in gene expression, morphology, or physiology arise in a cell, making its function increasingly specialized.The loss of specialization observed in dedifferentiation can be noted through changes in gene expression, physiology, function, proliferative activity, or morphology. While it can be induced in a laboratory setting through processes like direct reprogramming and the production of induced pluripotent stem cells, endogenous dedifferentiation processes also exist as a component of wound healing mechanisms.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of dedifferentiation in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of dedifferentiation in Pythagorean Numerology is: 2
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Translations for dedifferentiation
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"dedifferentiation." Definitions.net. STANDS4 LLC, 2024. Web. 8 May 2024. <https://www.definitions.net/definition/dedifferentiation>.
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