Definitions for cytarabine
cy·tara·bine

WiktionaryRate this definition:0.0 / 0 votes

1. cytarabinenoun

   A particular drug used in chemotherapy.

2. Etymology: Short for cytosine arabinoside.

WikipediaRate this definition:0.0 / 0 votes

1. Cytarabine

   Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma. It is given by injection into a vein, under the skin, or into the cerebrospinal fluid. There is a liposomal formulation for which there is tentative evidence of better outcomes in lymphoma involving the meninges.Common side effects include bone marrow suppression, vomiting, diarrhea, liver problems, rash, ulcer formation in the mouth, and bleeding. Other serious side effects include loss of consciousness, lung disease, and allergic reactions. Use during pregnancy may harm the baby. Cytarabine is in the antimetabolite and nucleoside analog families of medication. It works by blocking the function of DNA polymerase.Cytarabine was patented in 1960 and approved for medical use in 1969. It is on the World Health Organization's List of Essential Medicines.

WikidataRate this definition:0.0 / 0 votes

1. Cytarabine

   Cytarabine or cytosine arabinoside is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia and non-Hodgkin lymphoma. It is also known as Ara-C. It kills cancer cells by interfering with DNA synthesis. It is called cytosine arabinoside because it combines a cytosine base with an arabinose sugar. Cytosine normally combines with a different sugar, deoxyribose, to form deoxycytidine, a component of DNA. Certain sponges, where it was originally found, use arabinoside sugars to form a different compound. Cytosine arabinoside is similar enough to human cytosine deoxyribose to be incorporated into human DNA, but different enough that it kills the cell. This mechanism is used to kill cancer cells. Cytarabine is the first of a series of cancer drugs that altered the sugar component of nucleosides. Other cancer drugs modify the base.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Cytarabine

   A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)

How to pronounce cytarabine?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

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   Karen

   Australian

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   Australian

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Numerology

1. Chaldean Numerology

   The numerical value of cytarabine in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of cytarabine in Pythagorean Numerology is: 8

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Cytarabine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Cytarabine
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=cytarabine