Definitions for cycloheximide
cy·clo·hex·imide

WiktionaryRate this definition:0.0 / 0 votes

1. cycloheximidenoun

   an agricultural fungicide

WikipediaRate this definition:0.0 / 0 votes

1. Cycloheximide

   Cycloheximide is a naturally occurring fungicide produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effects by interfering with the translocation step in protein synthesis (movement of two tRNA molecules and mRNA in relation to the ribosome), thus blocking eukaryotic translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells studied in vitro (i.e. outside of organisms). It is inexpensive and works rapidly. Its effects are rapidly reversed by simply removing it from the culture medium.Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects (including birth defects and toxicity to sperm), cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Although it has been used as a fungicide in agricultural applications, this application is now decreasing as the health risks have become better understood. Because cycloheximide rapidly breaks down in a basic environment, decontamination of work surfaces and containers can be achieved by washing with a non-harmful alkali solution such as soapy water or aqueous sodium bicarbonate. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

WikidataRate this definition:0.0 / 0 votes

1. Cycloheximide

   Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effect by interfering with the translocation step in protein synthesis thus blocking translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells studied in vitro. It is inexpensive and works rapidly. Its effects are rapidly reversed by simply removing it from the culture medium. Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects, cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Although it has been used as a fungicide in agricultural applications, this application is now decreasing as the health risks have become better understood. Cycloheximide is degraded by alkali, decontamination of work surfaces and containers can be achieved by washing with a non-harmful alkali solution such as soap.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Cycloheximide

   Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.

How to pronounce cycloheximide?

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Numerology

1. Chaldean Numerology

   The numerical value of cycloheximide in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of cycloheximide in Pythagorean Numerology is: 9

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Cycloheximide
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Cycloheximide
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=cycloheximide