What does cryopyrin-associated periodic syndromes mean?
Definitions for cryopyrin-associated periodic syndromes
cry·opy·rin-asso·ci·at·ed peri·od·ic syn·dromes
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Wikipedia
cryopyrin-associated periodic syndromes
Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin 1β-mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system, and eyes. It encompasses a spectrum of three clinically overlapping autoinflammatory syndromes including familial cold autoinflammatory syndrome (FCAS, formerly termed familial cold-induced urticaria), the Muckle–Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease (NOMID, also called chronic infantile neurologic cutaneous and articular syndrome or CINCA) that were originally thought to be distinct entities, but in fact share a single genetic mutation and pathogenic pathway, and keratoendotheliitis fugax hereditaria in which the autoinflammatory symptoms affect only the anterior segment of the eye.
U.S. National Library of Medicine
Cryopyrin-associated Periodic Syndromes
A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 protein mutations.
Numerology
Chaldean Numerology
The numerical value of cryopyrin-associated periodic syndromes in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of cryopyrin-associated periodic syndromes in Pythagorean Numerology is: 9
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"cryopyrin-associated periodic syndromes." Definitions.net. STANDS4 LLC, 2024. Web. 2 May 2024. <https://www.definitions.net/definition/cryopyrin-associated+periodic+syndromes>.
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